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The mission of Metis is to reshape how we design and build infrastructure, and prepare engineers, in the Anthropocene. The Anthropocene will be defined by rapid technological, environmental, and social change, which will raise challenges for current infrastructure and engineering to meet changing needs. To build more resilient and sustainable systems that are capable of adapting to change in the 21st century and beyond, we will need to fundamentally rethink how and why we deploy and use infrastructure, and train engineers. The Metis Center seeks to establish an array of competencies to be able to respond to rapidly changing environments, technologies, and services, for a future marked by complexity and uncertainty.